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Clinical trials for Half Life

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    973 result(s) found for: Half Life. Displaying page 1 of 49.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2017-002793-39 Sponsor Protocol Number: 0451 Start Date*: 2018-03-13
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Abatacept Bone Effects in Psoriatic Arthritis with Bone Biomarker – ABEPSA_BB
    Medical condition: Psoriatic arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016785-88 Sponsor Protocol Number: AGO/2009/009 Start Date*: 2010-01-06
    Sponsor Name:University Hospital Ghent
    Full Title: Dexmedetomidine pharmacokinetics-pharmacodynamics in mechanically ventilated children with single-organ respiratory failure
    Medical condition: Patients admitted to the paediatric intensive care unit with single-organ respiratory failure
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000996-26 Sponsor Protocol Number: VAB1 Start Date*: 2016-09-01
    Sponsor Name:Region Ostergotland
    Full Title: Volumekinetics for hyperoncotic albumin in burn patients as well as for healthy subjects.
    Medical condition: Healthy adult volunteers and burn patients 3 to 10 Days after the injury.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023155-28 Sponsor Protocol Number: AGO/2010/006 Start Date*: 2011-02-14
    Sponsor Name:Ghent University Hospital
    Full Title: Dexmedetomidine pharmacokinetics-pharmacodynamics in mechanically ventilated neonates with single-organ respiratory failure (NEODEX)
    Medical condition: Patients admitted to the neonatal intensive care unit with single-organ respiratory failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004848 10053349 Pharmacokinetic study LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001135-20 Sponsor Protocol Number: Albumin Start Date*: 2015-04-28
    Sponsor Name:Södertälje sjukhus AB
    Full Title: Volume kinetics for 20% albumin in conscious and anaesthetized humans with and without inflammation.
    Medical condition: Healthy adult volunteers, healthy patients undergoing surgery under general anesthesia, and patients in a state of inflammation after having undergone surgery under general anaesthesia (within 24 h...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001655-41 Sponsor Protocol Number: 35RC19_8877_DIPLOID Start Date*: 2020-09-15
    Sponsor Name:CHU de Rennes
    Full Title: P-glypoprotein inhibition effect on the pharmacokinetics of two tacrolimus formulations: prolonged and extended-release
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000706-12 Sponsor Protocol Number: SUNNIFORECAST Start Date*: 2017-01-23
    Sponsor Name:Goethe University Frankfurt
    Full Title: A Phase 2, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Standard of Care in Subjects with Previously Untreated and Advanced (unresectable or metastatic) non-clear Cell ...
    Medical condition: The primary objective of the study is to compare the of OS rate at 12 months of Nivolumab combined with Ipilimumab to Standard of Care in patients with previously untreated and advanced non-clear c...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10038415 Renal cell carcinoma stage unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Prematurely Ended) NL (Ongoing) CZ (Completed) BE (Completed) ES (Ongoing) GB (GB - no longer in EU/EEA) FR (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003300-14 Sponsor Protocol Number: 74719 Start Date*: 2020-10-07
    Sponsor Name:Department of Cardiothoracic Surgery, Aalborg Universityhospital
    Full Title: Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery: a Randomized Controlled Pilot Trial
    Medical condition: Post Thoracotomy Pain Syndrome (PTPS)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001883-12 Sponsor Protocol Number: GI1616 Start Date*: 2016-09-14
    Sponsor Name:Herlev & Gentofte Hospital, Oncology Dept.
    Full Title: A PROSPECTIVE RANDOMIZED, OPEN-LABEL PHASE 2 STUDY OF IMMUNE CHECKPOINT INHIBITION, NIVOLUMAB WITH OR WITHOUT IPILIMUMAB IN COMBINATION WITH RADIATION THERAPY IN PRETREATED PATIENTS WITH METASTATIC...
    Medical condition: Patients with metastatic pancreatic cancer or metastatic biliary tract cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10033605 Pancreatic cancer metastatic LLT
    21.1 100000004864 10077846 Cholangiocarcinoma metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-001550-27 Sponsor Protocol Number: CACZ885A2201 Start Date*: 2006-10-20
    Sponsor Name:Novartis Farmaceútica
    Full Title: Estudio aleatorizado, doble ciego, multicéntrico, controlado con placebo, de grupos paralelos, con búsqueda de dosis, de 12 semanas de duración para evaluar la eficacia, la seguridad, y la tolerabi...
    Medical condition: Artritis reumatoide activa
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed) BE (Completed) FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001153-23 Sponsor Protocol Number: CAIN457I2401 Start Date*: 2022-12-29
    Sponsor Name:Novartis Pharma AG
    Full Title: A multicenter study of secukinumab, with a randomized double-blind, placebo-controlled withdrawal-retreatment period, to evaluate maintenance of response in participants with non-radiographic axial...
    Medical condition: Non-radiographic axial spondyloarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10076297 Non-radiographic axial spondyloarthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing) HU (Ongoing) DE (Ongoing) CZ (Ongoing) IT (Ongoing) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003759-13 Sponsor Protocol Number: GI1931 Start Date*: 2019-12-20
    Sponsor Name:Department of Oncology, Herlev & Gentofte
    Full Title: Phase 1/2 study in borderline resectable, locally advanced or metastatic pancreatic cancer to assess safety and potential efficacy of dual checkpoint inhibition in combination with gemcitabine and ...
    Medical condition: Locally advanced pancreatic cancer, non-resectable or borderline resectable, or metastatic pancreatic cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033606 Pancreatic cancer non-resectable LLT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033605 Pancreatic cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011000-34 Sponsor Protocol Number: CAIN457F2201 Start Date*: 2009-09-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 16-week multicenter, randomized, double-blind, placebo-controlled, parallel group, dose-finding study to evaluate the efficacy, safety and tolerability of subcutaneous AIN457 followed by an exten...
    Medical condition: Moderate to severe Rheumatoid Arthritis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) HU (Completed) BE (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2012-005330-10 Sponsor Protocol Number: 987654321 Start Date*: 2013-03-14
    Sponsor Name:Erasmus University Medical Centre
    Full Title: Maternal pharmacokinetics and pharmacodynamics of nicardipine (iv) during treatment of severe hypertension in pregnancy.
    Medical condition: Pregnant patients with preeclampsia (hypertension and protein/creatinine ratio ≥ 30mg/mmol or ≥ 300mg protein/24hours) complicated with severe hypertension (systolic bloodpressure ≥ 160mmHg and/or ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001715-31 Sponsor Protocol Number: EC-CG/AD-01/11 Start Date*: 2011-12-13
    Sponsor Name:Fundación para la Formación e Investigación Sanitaria de la Región de Murcia
    Full Title: Cytoreduction with or without intraoperative intraperitoneal hyperthermic chemotherapy (HIPEC) in patients with peritoneal carcinomatosis from ovarian cancer , fallopian tube or primary peritoneal ...
    Medical condition: Peritoneal carcinomatosis from ovarian cancer, fallopian tube or primary peritoneal carcinoma.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005500-18 Sponsor Protocol Number: VITCLEAR Start Date*: 2013-11-18
    Sponsor Name:King's College Hospital NHS Foundation Trust [...]
    1. King's College Hospital NHS Foundation Trust
    2. King's College London
    Full Title: A pharmacokinetic study: ranibizumab, aflibercept and the effect of vitrectomy
    Medical condition: Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    17.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    17.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002226-22 Sponsor Protocol Number: 2.0 Start Date*: 2019-04-30
    Sponsor Name:Medical University of Vienna
    Full Title: The Impact of Target Temperature Management on Drug Metabolism
    Medical condition: Patients after successful cardiopulmonary resuscitation who undergo target temperature management for 24h hours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004119-11 Sponsor Protocol Number: SPECT Start Date*: 2016-12-19
    Sponsor Name:Leiden University Medical Center
    Full Title: Study on half-dose Photodynamic therapy versus Eplerenone in chronic CenTRAl serous chorioretinopathy (SPECTRA trial)
    Medical condition: Chronic central serous chorioretinopathy
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10063118 Chorioretinopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002910-37 Sponsor Protocol Number: TEA Start Date*: 2019-10-07
    Sponsor Name:Erasmus MC
    Full Title: Study on the pharmacokinetic interaction between green tea and tamoxifen in patients with breast cancer. “the TEA study”
    Medical condition: Breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000217-21 Sponsor Protocol Number: 310816 Start Date*: 2018-03-22
    Sponsor Name:Aarhus University Hospital
    Full Title: Do use of torniquete reduce the impact of the antibiotic treatment during orthopedic treatment?
    Medical condition: Orthopedic infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10019095 Hallux Valgus correction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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